تنزيل ODONOGENESIS Platelet-rich fibrin (PRF) substance is a by-product of blood (plasma) that is rich in platelets. PRF, in short, is simply a byproduct of blood. It is exceptionally high in platelets and growth factors, the “signaling” molecules that allow communication between cells. PRF is a tool that significantly improves bone and soft tissue regeneration. Recently, its use has been advocated for regenerative periodontics and wound healing.
Platelet-rich fibrin is the new thing when it comes to surgery, with improved healing and immune support. The operation can have a faster and better recovery, with fewer post-operative complications. The application of platelet-rich fibrin during the implantation process enhanced the stability of the implants. The application of platelet-rich fibrin improves the stability of the implant in the first week of osseointegration. The biggest advantage of using platelet-rich fibrin is its complete absorption, thus avoiding the time of the second surgery, which is definitely a critical factor in elderly patients. This appears to be a minimally invasive technique with low risk and satisfactory clinical outcomes such as preventing complications or implant failure especially in age-related elderly patients.
In human,20 primary and 32 permanent teeth develop from the interaction of oral epithelial cells and underlying mesenchymal cells. Each developing tooth grows as an anatomically distinct unit, but the basic developmental process is similar for all teeth.
Odontogenesis is a highly co-ordinated and complex process which relies upon cell to cell interaction that results in the initiation and generation of the tooth. The gross histological processes are well documented, the mechanisms that are involved at a molecular level are only now beginning to be elucidated due to the revolution in molecular biological techniques that has occurred over the last decade. During their early development, tooth germs exhibit many morphological and molecular similarities with other developing epithelial appendages, such as hair follicles, mammary and salivary glands, lungs, kidneys, etc. The developing tooth germ, which is an experimentally accessible model for organogenesis, provides a powerful tool for elucidating the molecular mechanisms that control the development of these organs. There have been tremendous advances in recent years towards a better understanding of the regulation of tooth development.
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